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Pairwise additivity of energy components in protein-ligand binding: The HIV II protease-Indinavir case

An energy expansion (binding energy decomposition into n-body interaction terms for n ≥ 2) to express the receptor-ligand binding energy for the fragmented HIV II protease-Indinavir system is described to address the role of cooperativity in ligand binding. The outcome of this energy expansion is co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ucisik, Melek N., Dashti, Danial S., Faver, John C., Merz, Kenneth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Institute of Physics 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182082/
https://ncbi.nlm.nih.gov/pubmed/21895219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3624750
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