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Analyzing the components of the free-energy landscape in a calcium selective ion channel by Widom’s particle insertion method
The selectivity filter of the L-type calcium channel works as a Ca(2 +) binding site with a very large affinity for Ca(2 +) versus Na(+). Ca(2 +) replaces half of the Na(+) ions in the filter even when these ions are present in 1 μM and 30 mM concentrations in the bath, respectively. The energetics...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045419/ https://ncbi.nlm.nih.gov/pubmed/21303162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3532937 |
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