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High resolution deletion breakpoint mapping in the DMD gene by whole cosmid hybridization.

The locus DXS269 (P20) defines a deletion hotspot in the distal part of the Duchenne Muscular Dystrophy gene. We have cloned over 90 kilobase-pairs of genomic DNA from this region in overlapping cosmids. The use of whole cosmids as probes in a competitive DNA hybridization analysis proves a fast and...

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Detalhes bibliográficos
Main Authors: Blonden, L A, den Dunnen, J T, van Paassen, H M, Wapenaar, M C, Grootscholten, P M, Ginjaar, H B, Bakker, E, Pearson, P L, van Ommen, G J
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC318183/
https://ncbi.nlm.nih.gov/pubmed/2569720
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