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Germinal mosaicism increases the recurrence risk for 'new' Duchenne muscular dystrophy mutations.

In 288 Dutch and Belgian Duchenne and Becker muscular dystrophy families, the parental origin of 41 new deletion or duplication mutations was determined. Twenty seven of the new mutations occurred in the maternal X chromosome and nine in the grandmaternal and five in the grandpaternal X chromosome....

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Detalhes bibliográficos
Main Authors: Bakker, E, Veenema, H, Den Dunnen, J T, van Broeckhoven, C, Grootscholten, P M, Bonten, E J, van Ommen, G J, Pearson, P L
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1015693/
https://ncbi.nlm.nih.gov/pubmed/2810338
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