c-Met represents a potential therapeutic target for personalized treatment in Hepatocellular carcinoma

BACKGROUND: c-Met, a high-affinity receptor for Hepatocyte Growth Factor (HGF), plays a critical role in cancer growth, invasion and metastasis. Hepatocellular carcinoma (HCC) patients with an active HGF/c-Met signaling pathway have a significantly worse prognosis. Although targeting the HGF/c-Met p...

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Main Authors: You, Hanning, Ding, Wei, Dang, Hien, Jiang, Yixing, Rountree, C. Bart
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181384/
https://ncbi.nlm.nih.gov/pubmed/21618573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24450
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