CD55 Deficiency Protects against Atherosclerosis in ApoE-Deficient Mice via C3a Modulation of Lipid Metabolism

Atherosclerosis, the leading cause of death in the Western world, is driven by chronic inflammation within the artery wall. Elements of the complement cascade are implicated in the pathogenesis, because complement proteins and their activation products are found in the atherosclerotic plaque. We exa...

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Главные авторы: Lewis, Ruth D., Perry, Mark J., Guschina, Irina A., Jackson, Christopher L., Morgan, B. Paul, Hughes, Timothy R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2011
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Short Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181373/
https://ncbi.nlm.nih.gov/pubmed/21816131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.015
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