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Membrane-Bound Serine Protease Inhibitor HAI-1 Is Required for Maintenance of Intestinal Epithelial Integrity

Hepatocyte growth factor activator inhibitor type 1 (HAI-1), encoded by the serine protease inhibitor Kunitz type 1 (SPINT1) gene, is a membrane-bound serine protease inhibitor expressed in epithelial tissues. Mutant mouse models revealed that HAI-1/SPINT1 is essential for placental labyrinth format...

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Détails bibliographiques
Auteurs principaux: Kawaguchi, Makiko, Takeda, Naoki, Hoshiko, Shinri, Yorita, Kenji, Baba, Takashi, Sawaguchi, Akira, Nezu, Yuriko, Yoshikawa, Tsutomu, Fukushima, Tsuyoshi, Kataoka, Hiroaki
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181355/
https://ncbi.nlm.nih.gov/pubmed/21840293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.038
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