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Chemiluminescent detection of DNA: application for DNA sequencing and hybridization.

A non-radioactive DNA detection chemistry is described and its application is shown for DNA hybridization and standard dideoxy DNA sequencing. The method employes a biotin-streptavidin system which binds an enzyme specifically to a target DNA and upon exposure to substrate, the enzyme catalyzes a ch...

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Bibliografiske detaljer
Main Authors: Beck, S, O'Keeffe, T, Coull, J M, Köster, H
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC318099/
https://ncbi.nlm.nih.gov/pubmed/2762122
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