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Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress

p27(kip1) has been implicated in cell cycle regulation, functioning as an inhibitor of cyclin-dependent kinase activity. In addition, p27 was also shown to affect cell migration, with accumulation of cytoplasmic p27 associated with tumor invasiveness. However, the mechanism underlying p27 regulation...

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Main Authors: Nagano, Yoshito, Fukushima, Toru, Okemoto, Kazuo, Tanaka, Keiichiro, Bowtell, David DL, Ronai, Ze'ev A, Reed, John C, Matsuzawa, Shu-ichi
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180198/
https://ncbi.nlm.nih.gov/pubmed/21734459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.15.16912
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