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Conformational and thermodynamic consequences of the introduction of a nick in duplexed DNA fragments: an NMR study augmented by biochemical experiments.

NMR studies were carried out on various equimolar mixtures consisting of a combination of oligomers: d(ACGGCT) (I). d(pACGGCT) (Ia), d(TGCAGT) (II), d(AGCCGTACTGCA) (III), d(TGCAGTACGGCT) (IV). It is shown that I + II + III (MI) and Ia + II + III (M2) form stable duplexes with nicks in the centre of...

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Udgivet i:Nucleic Acids Res
Principais autores: Pieters, J M, Mans, R M, van den Elst, H, van der Marel, G A, van Boom, J H, Altona, C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1989
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2748334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.12.4551
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