Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α

We prepared and characterized golimumab, a human IgG1 tumor necrosis factor alpha (TNFα) antagonist monoclonal antibody chosen for clinical development based on its molecular properties. Golimumab was compared with infliximab, adalimumab and etanercept for affinity and in vitro TNFα neutralization....

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Detalhes bibliográficos
Main Authors: Shealy, David, Cai, Ann, Staquet, Kim, Baker, Audrey, Lacy, Eilyn R, Johns, Laura, Vafa, Omid, Gunn, George, Tam, Susan, Sague, Sarah, Wang, Dana, Brigham-Burke, Mike, Dalmonte, Paul, Emmell, Eva, Pikounis, Bill, Bugelski, Peter J, Zhou, Honghui, Scallon, Bernard, Giles-Komar, Jill
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180089/
https://ncbi.nlm.nih.gov/pubmed/20519961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.4.12304
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