Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α

We prepared and characterized golimumab, a human IgG1 tumor necrosis factor alpha (TNFα) antagonist monoclonal antibody chosen for clinical development based on its molecular properties. Golimumab was compared with infliximab, adalimumab and etanercept for affinity and in vitro TNFα neutralization....

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Библиографические подробности
Главные авторы: Shealy, David, Cai, Ann, Staquet, Kim, Baker, Audrey, Lacy, Eilyn R, Johns, Laura, Vafa, Omid, Gunn, George, Tam, Susan, Sague, Sarah, Wang, Dana, Brigham-Burke, Mike, Dalmonte, Paul, Emmell, Eva, Pikounis, Bill, Bugelski, Peter J, Zhou, Honghui, Scallon, Bernard, Giles-Komar, Jill
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2010
Предметы:
Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180089/
https://ncbi.nlm.nih.gov/pubmed/20519961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.4.12304
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