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Cation-exchange chromatography of monoclonal antibodies: Characterization of a novel stationary phase designed for production-scale purification
A novel cation-exchange resin, Eshmuno™ S, was compared to Fractogel(®) SO(3)(−) (M) and Toyopearl GigaCap S-650M. The stationary phases have different base matrices and carry specific types of polymeric surface modifications. Three monoclonal antibodies (mAbs) were used as model proteins to charact...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Landes Bioscience
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180086/ https://ncbi.nlm.nih.gov/pubmed/20559022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.4.12303 |
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