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Deletions of muscle mitochondrial DNA in mitochondrial myopathies: sequence analysis and possible mechanisms.

Forty per cent of patients with mitochondrial myopathies, a diverse group of multisystem diseases predominantly affecting skeletal muscle and the brain, have large deletions of a proportion of muscle mitochondrial DNA (mt DNA). These appeared to be identical in 13 of 28 cases, contained within the r...

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Autori principali: Holt, I J, Harding, A E, Morgan-Hughes, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC318006/
https://ncbi.nlm.nih.gov/pubmed/2748329
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