Stem Cell Marker (Nanog) and Stat-3 Signaling Promote MicroRNA-21 Expression and Chemoresistance in Hyaluronan/CD44-activated Head and Neck Squamous Cell Carcinoma Cells

MicroRNAs are often associated with the pathogenesis of many cancers including Head and Neck Squamous Cell Carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to play a critical role in tumor cell survival, chemoresistance and HNSCC progression. In this study we investigated matrix hyalur...

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Detalhes bibliográficos
Main Authors: Bourguignon, Lilly Y. W., Earle, Christine, Wong, Gabriel, Spevak, Christina C., Krueger, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179812/
https://ncbi.nlm.nih.gov/pubmed/21685938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.222
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