Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect

BACKGROUND: Mutations of genes affecting surfactant homeostasis, such as SFTPB, SFTPC and ABCA3, lead to diffuse lung disease in neonates and children. Haploinsufficiency of NKX2.1, the gene encoding the thyroid transcription factor-1 (TTF-1) - critical for lung, thyroid and central nervous system m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peca, Donatella, Petrini, Stefania, Tzialla, Chryssoula, Boldrini, Renata, Morini, Francesco, Stronati, Mauro, Carnielli, Virgilio P, Cogo, Paola E, Danhaive, Olivier
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179724/
https://ncbi.nlm.nih.gov/pubmed/21867529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-115
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