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Probabilistic modeling and analysis of the effects of extra-cellular matrix density on the sizes, shapes, and locations of integrin clusters in adherent cells

BACKGROUND: Regulation of integrin binding to the specific complementary sites on extra-cellular matrix (ECM) proteins plays a major role in cell adhesion and migration. In addition to regulating single integrin-ligand bonds by affinity modulation, cells regulate their adhesiveness by forming integr...

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Detalhes bibliográficos
Main Authors: Welf, Erik S, Naik, Ulhas P, Ogunnaike, Babatunde A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179437/
https://ncbi.nlm.nih.gov/pubmed/21827670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-1682-4-15
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