Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn(2+ )dissolution inside lysosomes

BACKGROUND: Large production volumes of zinc oxide nanoparticles (ZnONP) might be anticipated to pose risks, of accidental inhalation in occupational and even in consumer settings. Herein, we further investigated the pathological changes induced by ZnONP and their possible mechanism of action. METHO...

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Autori principali: Cho, Wan-Seob, Duffin, Rodger, Howie, Sarah EM, Scotton, Chris J, Wallace, William AH, MacNee, William, Bradley, Mark, Megson, Ian L, Donaldson, Ken
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179432/
https://ncbi.nlm.nih.gov/pubmed/21896169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-8-27
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