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Efficacy of Simple Short-Term in Vitro Assays for Predicting the Potential of Metal Oxide Nanoparticles to Cause Pulmonary Inflammation

BACKGROUND: There has been concern regarding risks from inhalation exposure to nanoparticles (NPs). The large number of particles requiring testing means that alternative approaches to animal testing are needed. OBJECTIVES: We set out to determine whether short-term in vitro assays that assess intri...

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Hlavní autoři: Lu, Senlin, Duffin, Rodger, Poland, Craig, Daly, Paul, Murphy, Fiona, Drost, Ellen, MacNee, William, Stone, Vicki, Donaldson, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: National Institute of Environmental Health Sciences 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649226/
https://ncbi.nlm.nih.gov/pubmed/19270794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11811
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