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Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice

Notch is a critical regulator of angiogenesis, vascular differentiation, and vascular integrity. We investigated whether Notch signaling affects macrophage function during retinal angiogenesis in mice. Retinal macrophage recruitment and localization in mice with myeloid-specific loss of Notch1 was a...

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Autori principali: Outtz, Hasina H., Tattersall, Ian W., Kofler, Natalie M., Steinbach, Nicole, Kitajewski, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179407/
https://ncbi.nlm.nih.gov/pubmed/21795743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-327015
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