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Genotype–phenotype correlations in patients with retinoblastoma and interstitial 13q deletions

Patients with an interstitial 13q deletion that contains the RB1 gene show retinoblastoma and variable clinical features. Relationship between phenotypic expression and loss of specific neighboring genes are unresolved, yet. We obtained clinical, cytogenetic and molecular data in 63 patients with an...

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Detalhes bibliográficos
Main Authors: Mitter, Diana, Ullmann, Reinhard, Muradyan, Artur, Klein-Hitpaß, Ludger, Kanber, Deniz, Õunap, Katrin, Kaulisch, Marc, Lohmann, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179359/
https://ncbi.nlm.nih.gov/pubmed/21505449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.58
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