Nell-1, a key Functional Mediator of Runx2, Partially Rescues Calvarial Defects in Runx2(+/−) Mice

Mesenchymal stem cell commitment to an osteoprogenitor lineage requires the activity of Runx2, a molecule implicated in the etiopathology of multiple congenital craniofacial anomalies. Through promoter analyses, we have recently identified a new direct transcriptional target of Runx2, Nell-1, a cran...

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Detalhes bibliográficos
Main Authors: Zhang, Xinli, Ting, Kang, Bessette, Catherine M, Culiat, Cymbeline T, Sung, Sang Jin, Lee, Haofu, Chen, Feng, Shen, Jia, Wang, James J, Kuroda, Shun'ichi, Soo, Chia
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179324/
https://ncbi.nlm.nih.gov/pubmed/20939017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.267
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