Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation

NELL1 is an extracellular protein inducing osteogenic differentiation and bone formation of osteoblastic cells. To elucidate the intracellular signaling cascade evoked by NELL1, we have shown that NELL1 protein transiently activates the MAPK signaling cascade, induces the phosphorylation of Runx2, a...

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Detalhes bibliográficos
Main Authors: Bokui, Nobuyuki, Otani, Takayuki, Igarashi, Koichi, Kaku, Junichiro, Oda, Mitsuo, Nagaoka, Tadahiro, Seno, Masaharu, Tatematsu, Kenji, Okajima, Toshihide, Matsuzaki, Takashi, Ting, Kang, Tanizawa, Katsuyuki, Kuroda, Shun’ichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959102/
https://ncbi.nlm.nih.gov/pubmed/18082140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.12.006
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