Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation

NELL1 is an extracellular protein inducing osteogenic differentiation and bone formation of osteoblastic cells. To elucidate the intracellular signaling cascade evoked by NELL1, we have shown that NELL1 protein transiently activates the MAPK signaling cascade, induces the phosphorylation of Runx2, a...

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Bibliografski detalji
Glavni autori: Bokui, Nobuyuki, Otani, Takayuki, Igarashi, Koichi, Kaku, Junichiro, Oda, Mitsuo, Nagaoka, Tadahiro, Seno, Masaharu, Tatematsu, Kenji, Okajima, Toshihide, Matsuzaki, Takashi, Ting, Kang, Tanizawa, Katsuyuki, Kuroda, Shun’ichi
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959102/
https://ncbi.nlm.nih.gov/pubmed/18082140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.12.006
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