Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma

PURPOSE: Despite aggressive therapies, median survival for malignant gliomas is less than 15 months. Patients with unmethylated O(6)-methylguanine–DNA methyltransferase (MGMT) fare worse, presumably because of temozolomide resistance. AdV-tk, an adenoviral vector containing the herpes simplex virus...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chiocca, E. Antonio, Aguilar, Laura K., Bell, Susan D., Kaur, Balveen, Hardcastle, Jayson, Cavaliere, Robert, McGregor, John, Lo, Simon, Ray-Chaudhuri, Abhik, Chakravarti, Arnab, Grecula, John, Newton, Herbert, Harris, Kimbra S., Grossman, Robert G., Trask, Todd W., Baskin, David S., Monterroso, Carissa, Manzanera, Andrea G., Aguilar-Cordova, Estuardo, New, Pamela Z.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2011
Sujets:
Original Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179270/
https://ncbi.nlm.nih.gov/pubmed/21844505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.35.5222
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