Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death

Although investigations of medieval plague victims have identified Yersinia pestis as the putative etiologic agent of the pandemic, methodological limitations have prevented large-scale genomic investigations to evaluate changes in the pathogen's virulence over time. We screened over 100 skelet...

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Bibliographic Details
Main Authors: Schuenemann, Verena J., Bos, Kirsten, DeWitte, Sharon, Schmedes, Sarah, Jamieson, Joslyn, Mittnik, Alissa, Forrest, Stephen, Coombes, Brian K., Wood, James W., Earn, David J. D., White, William, Krause, Johannes, Poinar, Hendrik N.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179067/
https://ncbi.nlm.nih.gov/pubmed/21876176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105107108
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