PKA phosphorylation couples hepatic inositol-requiring enzyme 1α to glucagon signaling in glucose metabolism

The endoplasmic reticulum (ER)-resident protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) is activated through transautophosphorylation in response to protein folding overload in the ER lumen and maintains ER homeostasis by triggering a key branch of the unfolded protein response. H...

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Hoofdauteurs: Mao, Ting, Shao, Mengle, Qiu, Yifu, Huang, Jialiang, Zhang, Yongliang, Song, Bo, Wang, Qiong, Jiang, Lei, Liu, Yi, Han, Jing-Dong J., Cao, Pengrong, Li, Jia, Gao, Xiang, Rui, Liangyou, Qi, Ling, Li, Wenjun, Liu, Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179066/
https://ncbi.nlm.nih.gov/pubmed/21911379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107394108
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