טוען...
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1α activation in pancreatic β-cells
Activation of inositol-requiring enzyme 1α (IRE1α) requires autophosphorylation to elicit the cellular unfolded protein response (UPR) and is functionally connected with insulin biosynthesis in pancreatic β-cells. We found that in pancreatic β-cells and primary islets the scaffold protein receptor f...
שמור ב:
| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940714/ https://ncbi.nlm.nih.gov/pubmed/20103773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000514 |
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