A crucial role for RACK1 in the regulation of glucose-stimulated IRE1α activation in pancreatic β-cells

Activation of inositol-requiring enzyme 1α (IRE1α) requires autophosphorylation to elicit the cellular unfolded protein response (UPR) and is functionally connected with insulin biosynthesis in pancreatic β-cells. We found that in pancreatic β-cells and primary islets the scaffold protein receptor f...

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Main Authors: Qiu, Yifu, Mao, Ting, Zhang, Yongliang, Shao, Mengle, You, Jia, Ding, Qiurong, Chen, Yan, Wu, Dongmei, Xie, Dong, Lin, Xu, Gao, Xiang, Kaufman, Randal J., Li, Wenjun, Liu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940714/
https://ncbi.nlm.nih.gov/pubmed/20103773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000514
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