Prostaglandin E(2) release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation

Astrocytes in the hypothalamus release prostaglandin E(2) (PGE(2)) in response to cell–cell signaling initiated by neurons and glial cells. Upon release, PGE(2) stimulates the secretion of gonadotropin-releasing hormone (GnRH), the neuropeptide that controls reproduction, from hypothalamic neuroendo...

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Hlavní autoři: Clasadonte, Jerome, Poulain, Pierre, Hanchate, Naresh K., Corfas, Gabriel, Ojeda, Sergio R., Prevot, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179065/
https://ncbi.nlm.nih.gov/pubmed/21896757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107533108
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