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Prostaglandin E(2) release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation

Astrocytes in the hypothalamus release prostaglandin E(2) (PGE(2)) in response to cell–cell signaling initiated by neurons and glial cells. Upon release, PGE(2) stimulates the secretion of gonadotropin-releasing hormone (GnRH), the neuropeptide that controls reproduction, from hypothalamic neuroendo...

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Detalhes bibliográficos
Main Authors: Clasadonte, Jerome, Poulain, Pierre, Hanchate, Naresh K., Corfas, Gabriel, Ojeda, Sergio R., Prevot, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179065/
https://ncbi.nlm.nih.gov/pubmed/21896757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107533108
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