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How does genome instability affect lifespan?
The genome is composed not only of genes but also of several noncoding functional elements (NOCs/ncFE, here I use NOCs), such as transcriptional promoters, enhancers, replication origins, centromeres and telomeres. rDNA has both gene and NOC characteristics. Thus, the rDNA encodes ribosomal RNAs, co...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178783/ https://ncbi.nlm.nih.gov/pubmed/21605287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2011.01519.x |
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