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Low dose antigen promotes induction of FOXP3 in human CD4(+) T cells

Low antigen dose promotes induction and persistence of Treg in mice, yet few studies have addressed the role of antigen dose in the induction of adaptive CD4(+)FOXP3(+) Treg in humans. To this end, we examined the level of FOXP3 expression in human CD4(+)CD25(−) T cells upon activation with autologo...

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Hlavní autoři: Long, S. Alice, Rieck, Mary, Tatum, Megan, Bollyky, Paul L., Wu, Rebecca P., Muller, Isabelle, Ho, Jhon-Chun, Shilling, Heather G., Buckner, Jane H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178710/
https://ncbi.nlm.nih.gov/pubmed/21865550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003880
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