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Essential Roles of BCCIP in Mouse Embryonic Development and Structural Stability of Chromosomes
BCCIP is a BRCA2- and CDKN1A(p21)-interacting protein that has been implicated in the maintenance of genomic integrity. To understand the in vivo functions of BCCIP, we generated a conditional BCCIP knockdown transgenic mouse model using Cre-LoxP mediated RNA interference. The BCCIP knockdown embryo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178617/ https://ncbi.nlm.nih.gov/pubmed/21966279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002291 |
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