Genetic Variants of TSLP and Asthma in an Admixed Urban Population

BACKGROUND: Thymic stromal lymphopoietin (TSLP), an IL7-like cytokine produced by bronchial epithelial cells is upregulated in asthma and induces dendritic cell maturation supporting a Th2 response. Environmental pollutants, including tobacco smoke and diesel exhaust particles upregulate TSLP sugges...

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Detalhes bibliográficos
Main Authors: Liu, Mengling, Rogers, Linda, Cheng, Qinyi, Shao, Yongzhao, Fernandez-Beros, Maria Elena, Hirschhorn, Joel N., Lyon, Helen N., Gajdos, Zofia K. Z., Vedantam, Sailaja, Gregersen, Peter, Seldin, Michael F., Bleck, Bertram, Ramasamy, Adaikalavan, Hartikainen, Anna-Liisa, Jarvelin, Marjo-Riitta, Kuokkanen, Mikko, Laitinen, Tarja, Eriksson, Johan, Lehtimäki, Terho, Raitakari, Olli T., Reibman, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178593/
https://ncbi.nlm.nih.gov/pubmed/21966427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025099
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