Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

The rise in type 1 diabetes (T1D) incidence in recent decades is probably related to modifications in environmental factors. Viruses are among the putative environmental triggers of T1D. The mechanisms regulating beta cell responses to viruses, however, remain to be defined. We have presently clarif...

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Detaylı Bibliyografya
Asıl Yazarlar: Colli, Maikel L., Nogueira, Tatiane C., Allagnat, Florent, Cunha, Daniel A., Gurzov, Esteban N., Cardozo, Alessandra K., Roivainen, Merja, Op de beeck, Anne, Eizirik, Decio L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178579/
https://ncbi.nlm.nih.gov/pubmed/21977009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002267
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