Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

High-grade gliomas (World Health Organization grade III anaplastic astrocytoma and grade IV glioblastoma multiforme), the most prevalent primary malignant brain tumors, display a cellular hierarchy with self-renewing, tumorigenic cancer stem cells (CSCs) at the apex. While the CSC hypothesis has bee...

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Main Authors: Lathia, Justin D., Gallagher, Joseph, Myers, Jay T., Li, Meizhang, Vasanji, Amit, McLendon, Roger E., Hjelmeland, Anita B., Huang, Alex Y., Rich, Jeremy N.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178553/
https://ncbi.nlm.nih.gov/pubmed/21961046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024807
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