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Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala

Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear memories, currently remains unknown. Here we provide the first evidence that...

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書誌詳細
主要な著者: Jarome, Timothy J., Werner, Craig T., Kwapis, Janine L., Helmstetter, Fred J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178530/
https://ncbi.nlm.nih.gov/pubmed/21961035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024349
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