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An antibody against the surfactant protein A (SP-A)-binding domain of the SP-A receptor inhibits T cell-mediated immune responses to Mycobacterium tuberculosis

Surfactant protein A (SP-A) suppresses lymphocyte proliferation and IL-2 secretion, in part, by binding to its receptor, SP-R210. However, the mechanisms underlying this effect are not well understood. Here, we studied the effect of antibodies against the SP-A-binding (neck) domain (α-SP-R210n) or n...

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Hlavní autoři: Samten, Buka, Townsend, James C., Sever-Chroneos, Zvjezdana, Pasquinelli, Virginia, Barnes, Peter F., Chroneos, Zissis C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Society for Leukocyte Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178510/
https://ncbi.nlm.nih.gov/pubmed/18443188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1207835
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