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Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms

Ubiquitin modification of many cellular proteins targets them for proteasomal degradation, but in addition can also serve non-proteolytic functions. Over the last years, a significant progress has been made in our understanding of how modification of the substrates of the ubiquitin system is regulat...

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Detalhes bibliográficos
Main Authors: de Bie, P, Ciechanover, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178436/
https://ncbi.nlm.nih.gov/pubmed/21372847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.16
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