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DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity

Death-associated protein kinase (DAPK) is a key player in several modes of neuronal death/injury and has been implicated in the late-onset Alzheimer's disease (AD). DAPK promotes cell death partly through its effect on regulating actin cytoskeletons. In this study, we report that DAPK inhibits...

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Detalhes bibliográficos
Main Authors: Wu, P-R, Tsai, P-I, Chen, G-C, Chou, H-J, Huang, Y-P, Chen, Y-H, Lin, M-Y, Kimchi, A, Chien, C-T, Chen, R-H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178434/
https://ncbi.nlm.nih.gov/pubmed/21311567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.2
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