Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency

OBJECTIVE: Haptoglobin (Hp) is upregulated in both inflammation and obesity. The low chronic inflammatory state, caused by massive adipose tissue macrophage (ATM) infiltration found in obesity, and low adiponectin have been implicated in the development of insulin resistance and hepatosteatosis. The...

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Bibliographic Details
Main Authors: Lisi, Simonetta, Gamucci, Olimpia, Vottari, Teresa, Scabia, Gaia, Funicello, Marcella, Marchi, Matilde, Galli, Giulia, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Pinchera, Aldo, Santini, Ferruccio, Maffei, Margherita
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2011
Subjects:
Obesity Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178294/
https://ncbi.nlm.nih.gov/pubmed/21873550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1536
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