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Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency

OBJECTIVE: Haptoglobin (Hp) is upregulated in both inflammation and obesity. The low chronic inflammatory state, caused by massive adipose tissue macrophage (ATM) infiltration found in obesity, and low adiponectin have been implicated in the development of insulin resistance and hepatosteatosis. The...

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Détails bibliographiques
Auteurs principaux: Lisi, Simonetta, Gamucci, Olimpia, Vottari, Teresa, Scabia, Gaia, Funicello, Marcella, Marchi, Matilde, Galli, Giulia, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Pinchera, Aldo, Santini, Ferruccio, Maffei, Margherita
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178294/
https://ncbi.nlm.nih.gov/pubmed/21873550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1536
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