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Simultaneous quantification of nicotine, opioids, cocaine, and metabolites in human fetal postmortem brain by liquid chromatography tandem mass spectrometry

A validated method for simultaneous LCMSMS quantification of nicotine, cocaine, 6-acetylmorphine (6AM), codeine, and metabolites in 100 mg fetal human brain was developed and validated. After homogenization and solid-phase extraction, analytes were resolved on a Hydro-RP analytical column with gradi...

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Main Authors: Shakleya, Diaa M., Huestis, Marilyn A.
格式: Artigo
語言:Inglês
出版: 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178103/
https://ncbi.nlm.nih.gov/pubmed/19229524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-009-2661-8
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