Influence of C-159T SNP of the CD14 gene promoter on lung function in smokers with chronic bronchitis

CD14, a co-receptor for endotoxin, plays a significant role in the inflammatory response to this environmentally important pollutant. The C-159T single nucleotide polymorphism (SNP) in the CD14 gene promoter is reported to affect expression of CD14, with TT homozygous persons having higher CD14 expr...

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Main Authors: Zhou, Haibo, Alexis, Neil E, Almond, Martha, Donohue, James, LaForce, Craig, Bromberg, Philip A., Peden, David B.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178042/
https://ncbi.nlm.nih.gov/pubmed/19361972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmed.2009.03.007
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