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Inferring mechanisms from dose-response curves

The steady state dose-response curve of ligand-mediated gene induction usually appears to precisely follow a first-order Hill equation (Hill coefficient equal to 1). Additionally, various cofactors/reagents can affect both the potency and the maximum activity of gene induction in a gene-specific man...

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Podrobná bibliografie
Hlavní autoři: Chow, Carson C., Ong, Karen M., Dougherty, Edward J., Simons, S. Stoney
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177954/
https://ncbi.nlm.nih.gov/pubmed/21187235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381270-4.00016-0
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