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Focal adhesions and Ras are functionally and spatially integrated to mediate IL-1 activation of ERK
In connective tissue cells, IL-1-induced ERK activation leading to matrix metalloproteinase (MMP)-3 expression is dependent on cooperative interactions between focal adhesions and the endoplasmic reticulum (ER). As Ras can be activated on the ER, we investigated the role of Ras in IL-1 signaling and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177576/ https://ncbi.nlm.nih.gov/pubmed/21719512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-183459 |
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