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Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B
A hallmark of mitosis is the appearance of high levels of histone phosphorylation, yet the roles of these modifications remain largely unknown. Here we demonstrate that histone H3 phosphorylated at threonine 3 is directly recognized by an evolutionarily conserved binding pocket in the BIR domain of...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177562/ https://ncbi.nlm.nih.gov/pubmed/20705815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189505 |
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