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Accessibility of N-acyl-d-mannosamines to N-acetyl-d-neuraminic acid aldolase

N-Acetyl-d-neuraminic acid (NeuNAc) aldolase is an important enzyme for the metabolic engineering of cell surface NeuNAc using chemically modified d-mannosamines. To explore the optimal substrates for this application, eight N-acyl derivatives of d-mannosamine were prepared, and their accessibility...

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Detalhes bibliográficos
Main Authors: Pan, Yanbin, Ayani, Tiffany, Nadas, Janos, Wen, Shouming, Guo, Zhongwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177532/
https://ncbi.nlm.nih.gov/pubmed/15280054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2004.05.028
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