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An Integrin-binding N-terminal Peptide Region of TIMP-2 Retains Potent Angio-Inhibitory and Anti-tumorigenic Activity In Vivo
Tissue inhibitor of metalloproteinases-2 (TIMP-2) inhibits angiogenesis by several mechanisms involving either MMP inhibition or direct endothelial cell binding. The primary aim of this study was to identify the TIMP-2 region involved in binding to the previously identified receptor integrin α3β1, a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177407/ https://ncbi.nlm.nih.gov/pubmed/21871510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.08.010 |
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