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Renal collecting system growth and function depend upon embryonic γ1 laminin expression

In order to understand the functions of laminins in the renal collecting system, the Lamc1 gene was inactivated in the developing mouse ureteric bud (UB). Embryos bearing null alleles exhibited laminin deficiency prior to mesenchymal tubular induction and either failed to develop a UB with involutio...

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Main Authors: Yang, Dong-Hua, McKee, Karen K., Chen, Zu-Lin, Mernaugh, Glenda, Strickland, Sidney, Zent, Roy, Yurchenco, Peter D.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177319/
https://ncbi.nlm.nih.gov/pubmed/21903675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071266
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