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Renal collecting system growth and function depend upon embryonic γ1 laminin expression

In order to understand the functions of laminins in the renal collecting system, the Lamc1 gene was inactivated in the developing mouse ureteric bud (UB). Embryos bearing null alleles exhibited laminin deficiency prior to mesenchymal tubular induction and either failed to develop a UB with involutio...

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Hlavní autoři: Yang, Dong-Hua, McKee, Karen K., Chen, Zu-Lin, Mernaugh, Glenda, Strickland, Sidney, Zent, Roy, Yurchenco, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177319/
https://ncbi.nlm.nih.gov/pubmed/21903675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071266
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